“TITLE: Renal Practical AIM: To demonstrate how pH and osmolarity are regulated by the kidneys.”

The kidney has many functions and important role in homeostasis. It maintains a relatively balanced internal environment by employing homeostatic mechanism.

One of its functions is to maintain and regulate the pH and osmolarity within the body.

In this practical, the pH regulation and osmolarity regulation was investigated and this was done by studying the total estimated excretion of H+ and NH4+ ions.

Renal compensation is the way in which the renal system provides support in maintaining the pH. This occurs when there is a change in renal rates of hydrogen ion and bicarbonate ions. These two products are produced from the dissociation of carbonic acid buffer which is a product of CO2 and H2O.

On normal conditions, the body generates enough organic acid and fixed acids to add 100mEq of H+ to extracellular fluid each day. This results in equivalent number of hydrogen ions bein…(short extract)