During the last 5 weeks, you have explored various body systems: neurological, cardiovascular, respiratory, and hematological. These four
systems work together along with other body systems to complete a myriad of functions. For this reason, when disorders occur within one body
system, it can create potentially devastating effects throughout the entire body. For instance, Parkinson’s disease is a disorder of the
central nervous system, yet its alterations actually affect multiple body systems from the cardiovascular system to the gastrointestinal
system. In this Assignment, you examine alterations associated with disorders, as well as the impact of the alterations on multiple body
systems.
To prepare: Use the topic below
•Chronic obstructive pulmonary disease (COPD)
•Identify alterations associated with your selected disorder. Consider the pathophysiology of the alterations. Think about how these
alterations produce pathophysiological changes in at least two body systems.
•Reflect on how patient factors such as genetics, gender, ethnicity, age, and behavior might impact the pathophysiology of the alterations
you identified, as well as the diagnosis and treatment of your selected disorder.
•Review the “Mind maps—Dementia, Endocarditis, and Gastro-oesophageal Reflux Disease (GERD)” media in the Week 2 Learning Resources. Use the
examples in the media as a guide to construct a mind map for the disorder you selected. Consider the epidemiology and clinical presentation
of your selected disorder.
To complete:
Develop a 5- to 10-slide PowerPoint presentation that addresses the following:
•Describe your selected disorder, as well as associated alterations. Explain the pathophysiology of the alterations, including changes that
occur in at least two body systems.
•Explain how genetics, gender, ethnicity, age, and behavior might impact the pathophysiology of the alterations you identified, as well as
diagnosis and treatment of your selected disorder.
•Construct a mind map for the disorder you selected. Include the epidemiology, pathophysiology of alterations, risk factors, and clinical
presentation, as well as the diagnosis and treatment of the disorder.
do COPD
Resources must be 5 years or younger and must be retrievable by instructor and students
Resources:
Required Resources
Note: To access this week’s required library resources, please click on the link to the Course Readings List, found in the Course Materials
section of your Syllabus.
Readings
•Huether, S. E., & McCance, K. L. (2012). Understanding pathophysiology (Laureate custom ed.). St. Louis, MO: Mosby. ◦Chapter 33, “Structure
and Function of the Digestive System”
This chapter provides information relating to the structure and function of the digestive system. It covers the gastrointestinal tract and
accessory organs of digestion.
◦Chapter 34, “Alterations of Digestive Function”
This chapter presents information relating to disorders of the gastrointestinal tract and accessory organs of digestion. It also covers the
pathogenesis, clinical manifestations, evaluation, and treatment of gastroesophageal reflux disease, gastritis, peptic ulcer disease,
inflammatory bowel disease, and irritable bowel syndrome.
◦Chapter 35, “Alterations of Digestive Function in Children”
This chapter presents information relating to disorders of the gastrointestinal tract and liver that affect children. It focuses on
congenital impairment, inflammatory disorders, metabolic disorders, as well as the impairment of digestion, absorption, and nutrition.
•McPhee, S. J., & Hammer, G. D. (2012). Pathophysiology of disease: An introduction to clinical medicine (Laureate Education, Inc., custom
ed.). New York, NY: McGraw-Hill Medical. ◦Chapter 13, “Gastrointestinal Disease”
This chapter provides a foundation for exploring gastrointestinal disorders by reviewing the structure and function of the GI tract. It also
describes mechanisms of regulation of GI tract disorders such as acid-peptic disease, inflammatory bowel disease, and irritable bowel
syndrome.
◦Chapter 14, “Liver Disease”
This chapter reviews the structure and function of the liver. It then explores the clinical presentation, etiology, pathogenesis, pathology,
and clinical manifestations of three liver disorders: acute hepatitis, chronic hepatitis, and cirrhosis.
◦Chapter 15, “Disorders of the Exocrine Pancreas”
This chapter begins by reviewing the anatomy, histology, and physiology of the exocrine pancreas. It then examines the clinical presentation,
etiology, pathology, pathogenesis, and clinical manifestations of acute and chronic pancreatitis, pancreatic insufficiency, and pancreatic
cancer.
•Gasiorowska, A., Poh, C. H., & Fass, R. (2009). Gastroesophageal reflux disease (GERD) and irritable bowel syndrome (IBS)—Is it one disease
or an overlap of two disorders? Digestive Diseases and Sciences, 54(9), 1829–1834.
Retrieved from the Walden Library databases.
This article examines the similarities between gastroesophageal reflux disease and irritable bowel syndrome. It focuses on symptoms presented
in patients with the disorders, as well as management and treatment options.
Media
•Laureate Education, Inc. (Executive Producer). (2012c). The gastrointestinal system. Baltimore, MD: Author.
This media presentation outlines the pathophysiology of the gastrointestinal system and associated alterations.
Optional Resources
•American Liver Foundation (2011). Retrieved from https://www.liverfoundation.org/
•National Digestive Diseases Information Clearinghouse. (2012). Retrieved from https://digestive.niddk.nih.gov/index.aspx

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